Revolution in Medical Science: Medicines will be used according to the patient's DNA

 


An important scientific report says that a new era is about to begin in the world of medicine where every patient will be given medicine according to his DNA.


Some medications can be ineffective or even fatal to some because not all bodies work the same way and there are subtle differences.

The British Pharmacological Society and the Royal College of Physicians say that by doing genetic testing we can estimate how a drug will affect a single person. These genetic tests will be available at the UK's National Health Service from next year. 

A person's DNA or genetic code is important to a booklet about his body, how the human body works. The use of drugs according to DNA is called pharmacogenomics.

The treatment helped Liverpool-born Jane Burns recover from two-thirds of the skin damage caused by epilepsy. When she was 19, she was introduced to the drug carbamazepine, which is used to treat epilepsy. 

Two weeks later he developed a skin rash and when he started having a fever his parents took him to the doctor. The next day, his skin began to be affected by skin wounds. 


"I remember when I woke up I had blisters all over my skin, it was like a scary movie, I felt like I was burning," Jane said.

She was diagnosed with Stevens-Johnson Syndrome, an epileptic seizure that affected her skin, and is most common in people with a congenital genetic predisposition.

Mrs Burns says she was "very lucky" and supports the pharmacogenomic test.

"It would be great if it could save your life," she says.


Almost everyone is affected

What may have happened to the gene may seem strange and rare, but Professor Mark Callefield, president-elect of the British Pharmacological Society, says that 99.5% of people have a genome in their genetic code or DNA. That if we use the wrong medicine it is either ineffective or harmful.

Codeine does not reduce pain in more than 5 million people in the UK. Because their DNA or genetic code does not contain instructions to convert a drug called codeine into morphine and relieve patients of pain, this drug is useless to them.

Similarly, according to scientists, one out of every 500 people has a genetic code or DNA that increases their risk of hearing loss if they use the antibiotic gentamicin. 

Pharmacogenomic is already used for a few drugs. 

In the past, five to seven percent of people infected with HIV have been exposed to the harmful effects of abacavur, a drug for the disease, and some of them have even died. If a patient's DNA is now analyzed before prescribing the drug, the risk of the drug being ineffective and harmful is reduced to zero.

Scientists have looked at the 100 most recommended prescriptions in the UK. According to their report, they already have the technology to adapt forty of these versions to the individual needs of the people.

This genetic analysis can be done at 100 pounds and the test will be done with a blood or saliva sample. 

Initially, he thought the test would be on the prescription of one of the 40 drugs. In the future, it is expected that the test will be performed at the time of birth of any child, or that the test will be part of a routine check at the age of 50.


Accurate information 

Sir Munir Pir Mohammed, a professor at the University of Liverpool, said: 

"Actually what we are going to do is the beginning of a new era in the world of medicine because we are all different and drugs affect us in different ways," he said.

"As we get older, we have to take more medicine," he said. And there's a 70 percent chance that by the time you reach 70, there will be at least one drug that matches our individual DNA.

"This is a revolution in the world of medicine," said Lord David Prior, chairman of the National Health Services England. 

"Pharmacogenomics is the future," he said, adding that "it can help us in 2022 to provide a new and modern healthcare system tailored to the needs of each individual."


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